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Documents coming from the Food and Drug Administration by this writer under the Freedom of Information Act states that no evidence exists that XANAX treats panic or anxiety. However, the said product has FDA license for treating both conditions. Further, serious side effects have been reported even from the dosages administered under the relative short-term clinical trials that XANAX undergone in order to obtain FDA approval.
As one evaluates the studies, memorandums and statistics that support the safety and efficacy of XANAX, probing questions as to the legality of the direction of the American health care process are inescapable. Panic disorder with the use of Xanax was approved without dangerous side effects. Xanax is only indicated for short-term use with ten weeks being the longest because there is no data that suggest that is it safe to be use in a long period of time. But FDA approved the drug in higher dosage like up to 10 mg per day.
There are three trials made that they call study 4404, 4412 and Study 4432 that being conducted sequentially.
In study 4404, a 10-week flexible dose, single-centered, parallel, double blind and placebo controlled multicenter for around 8- week trial. In this trial, Xanax treatment is worst than no treatment at all. When it comes to panic attack, there is only one important difference and that 5 mg of Xanax is to be more effective than no treatment at all.
In study 4412, it is parallel, double blind and placebo-controlled for also 8 week trial. One comment being made was that it is disconcerting to note that Dupont Center have the largest sample size and it showed a larger decrease in number of panic attacks for the placebo group. In study 4432, a 6 week trial that is blind, placebo-controlled multi center trial and parallel. The results are not in favor of Xanax and it also suggested that a dose of 6 mg per day is a way too high.